Soy
Isoflavones and Bone Resorption
Article Summary:
This study examines the effect of soy isoflavones on bone mineral
density, bone formation, bone resporption, and bone mineral content.
The clinical study was completely randomized and was also placebo
controlled to ensure the quality of the results. Nineteen postmenopausal
women were given 110 mg of soy isoflavone supplementation daily
for a total of 6 months. During the period of supplementation, the
women were found to have a significant decrease in bone resorption
while the placebo group were not. Compared to the placebo group,
there was a significant difference in mean HP excretion levels,
with the soy isoflavone supplementation group having much less.
Also, the mean bone mineral density in the spine, specifically at
bones L2 and L3, was outstandingly greater in the soy isoflavon
supplementation group when compared to the placebo group. While
further studies need to be conducted to figure out the effect of
soy
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isoflavones on all aspects of bone, this study concludes that supplementation
significantly reduces bone resorption and increases bone mineral
density in the spine in postmenopausal women.
Authors:
Harkness LS, Fiedler K, Sehgal AR, Oravec D, Lerner E.
Institution:
Case Western Reserve University, Cleveland, Ohio 44109, USA.
Country of Publication:
United States
Source:
J Womens Health (Larchmt). 2004. NIH |
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