Calcium Citrate Supplementation

Stone forming risk of calcium citrate supplementation in healthy postmenopausal women.

Article Summary:

The article is a review of the study that evaluated the effect of calcium citrate supplementation alone or in combination with potassium citrate on the stone forming propensity in health postmenopausal women. There are 18 postmenopausal women without stone participated in a randomized trial. The trial involved four phases; treatments included placebo, calcium citrate, potassium citrate, and calcium citrate and potassium citrate. The study shows with the combination of both calcium citrate and potassium citrate the urinary calcium remained high, urinary citrate increased further, and with a decrease in urinary oxalate from calcium citrate. The study concludes that calcium citrate supplementation does not increase the risk of stone formation in healthy postmenopausal women, and the combination of calcium citrate and potassium citrate may even provide additional protection against the formation of

uric acid and calcium oxalate stones in postmenopausal women.

Authors:

Sakhaee K, Poindexter JR, Griffith CS, Pak CY.

Insititution:

Center for Mineral Metabolism and Clinical Research, University of Texas Southwestern Medical Center.

Country of Publication:

United States

Source:

J Urol. 172(3):958-61, 2004 September. NIH

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