Benefits of Licorice Root in Treating Menopausal Depression

Inhibition of serotonin re-uptake by licorice constituents.

 

Article Summary:

A review of a study which examines the effects of serotonin re-uptake and its relation to depression in pre- and postmenopausal women. Blocking or reducing serotonin re-uptake alleviates depression. The results from this study show that the licorice root derivatives glabridin and glabrene inhibited serotonin re-uptake by 60% and 47%, respectively. The ability for these licorice root constituents to reduce serotonin re-uptake demonstrates their benefits in treating mild to moderate depression in menopausal women.

Authors:

Ofir R, Tamir S, Khatib S, Vaya J.


Institution:

Hatzeva Research and Development Center, Jacob Blaustein Institute for Desert Research, Ben Gurion University of the Negev, Beer Sheva 84105, Israel.

Country of Publication:

Israel

Source:

J Mol Neurosci. 2003 Apr;20(2):135-40. NIH.

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