Red Clover and Hot Flushes Isoflavones from red clover significantly reduce menopausal hot flush symptoms compared with placebo.
Article Summary: This is a review on the study that investigates the effectiveness and safety of red clover isoflavone dietary supplement on hot flush frequency in postmenopausal women. The study included a randomized, double blind, placebo-controlled trial with 30 participants. These participants were women with more than 12 months amenorrhoea and were experiencing more than five flushes per day. For each woman, single blind placebo tablets were given for 4 weeks and were subsequently randomized to either placebo or 80 mg isoflavones for 12 more weeks. Both the Greene Climacteric Scale Score and the decrase in number of hot flushes per day were measured. The results showed that the frequency of hot flushes in the isoflavone group decreased by 44% and its Greene score decreased by 13%, while the placebo group remained unchanged for Greene score and |
only 16% decrease on hot flush frequency. The study suggested that isoflovone treatment resulted in a significant reduction in hot flushes and demonstrated the effectiveness of the red clover isoflavone dietary supplements. Authors: Insititution: Country of Publication: Source:
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