Red
Clover and Osteoblastic Cell Activity
Quoted Article:
“Different extracts from red clover (Trifolium pratense L.)
were tested for their ability to stimulate the activity of osteoblastic
osteosarcoma cells (HOS58). As a key marker of osteoblasticity we
chose the activity of alkaline phosphatase (ALP). Whereas butanol
and methanol extracts had no influence on either ALP or cellular
protein production, enzyme activity was increased significantly
on incubation with chloroform extracts. All extracts were analysed
for isoflavone content. The data clearly suggest a role for red
clover isoflavonoids in the stimulation of osteoblastic cell activity.”
Authors:
Wende K, Krenn L, Unterrieder I, Lindequist U.
Institution:
Institute of Pharmacy, University of Greifswald, Greifswald, Germany.
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Country
of Publication:
Germany
Source:
Planta Med. 2004 Oct;70(10):1003-5.
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