Vitamin
D Receptor and Surgical Menopause
Article Summary:
A review of a study evaluating a common form of the Vitamin D receptor
gene and its effects on female reproductive functions, specifically
menopause. The Vitamin D receptor proved to be non-influential in
altering the timing of natural menopause as well as having no effect
on pregnancies in the 1,058 women that were studied. Yet, women
found to have at least one mutant form of the Vitamin D receptor
gene demonstrated a significantly decreased risk for experiencing
surgical menopause, such as premenopausal hysterectomy. These results
were found in a large group of Caucasian women.
Authors:
Grimm C, Tempfer CB, Walch K, Reinthaller A, Tomovski C, Huber JC,
Leodolter S, Hefler LA.
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Institution:
Department of Obstetrics and Gynecology, University of Vienna Medical
School, Vienna, Austria.
Country of Publication:
Austria
Source:
Maturitas. 2005 Jun 16;51(2):135-9. NIH.
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