Vitamins
D and K on Bone Mineral Density
Article Summary:
The study aimed to determine the effect of administering vitamin
D3 and vitamin K2 on bone mineral density of the lumbar spine in
postmenopausal women with osteoporosis. 92 women, all of which were
more than 5 years after menopause, were used in the study. The women
were all roughly similar in age, initial bone mineral content, years
since menopause, and body mass index. The women were randomly divided
into four groups: a group of 29 women receiving 0.75 micrograms
of vitamin D3 daily, a group of 22 women receiving 45 mg of vitamin
K2 daily, a group of 21 women receiving both vitamin D3 and vitamin
K2 daily, and a group of 20 women receiving 2 grams of calcium daily.
At the beginning of the study the women's bone mineral density of
the lumbar spine was measured. These measurements were then repeated
after 1 year and 2 years of treatment.
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The
results showed a significant increase in bone mineral density in
both of individual vitamin groups when compared with the calcium
group. Furthermore, there was an even more significant increase
in bone mineral density in the group receiving both vitamin D3 and
vitamin K2 when compared with the other three groups. These findings
indicate that taking vitamin D3 and vitamin K2 in combination is
highly beneficial in increasing bone mineral density of the lumbar
spine in postmenopausal women with osteoporosis.
Authors:
Iwamoto J, Takeda T, Ichimura S.
Institution:
Department of Sports Clinic, Keio University School of Medicine,
35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.
Country of Publication:
Japan
Source:
J Orthop Sci. 2000;5(6):546-51. NIH
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