Vitamin K and Bone Formation

Promotion of bone formation by fermented soybean intake in premenopausal women.


Article Summary:

This trial was conducted to determine the relationship between the dietary intake of vitamin K2 and bone health in premenopausal women. Fermented soybeans were used in the study due to the fact that they contain high amounts of vitamin K2. Four groups were randomly formed out of 73 healthy premenopausal women: group 1 receiving no intake, group 2 receiving intake once per month, group 3 receiving intake once per week, and group 4 receiving intake three times per week. This was carried out for 1 year, during which the women all took the fermented soybeans at lunchtime. Stiffness index by quantitative ultrasound and bone turnover markers was measured before the study, at the 6-month mark, and after the 1-year period. Through a number of tests, logistic regression analysis showed that group 4 had a reduced risk of reduction of boen formation markers when compared to group 1. This study concludes that vitamin K2 is beneficial and may contribute to the promotion of bone formation.



Authors:

Katsuyama H, Ideguchi S, Fukunaga M, Fukunaga T, Saijoh K, Sunami S.

Institution:

Department of Public Health, Kawasaki Medical School, Kurashiki 701-0192, Japan.

Country of Publication:

Japan

Source:

J Nutr Sci Vitaminol (Tokyo). 2004 Apr;50(2):114-20

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