Menopause and Hormones

Understanding the hormonal cycle and how hormones affect the body is an important part of treating Menopause. If you can visualize what your body is going through, in short, if you are body conscious, then you will have more success at treating and coping with Menopause.

The Cycle
There are thousands of tiny sacs within each ovary called follicles. When a woman experiences her first period, she has close to a ½ million follicles, each of which are filled with eggs. Early in each menstrual cycle, one egg will begin to prepare for the journey to the uterus. At mid-cycle, the follicle will burst open, and the egg will then pass into the fallopian tube, and on into the uterus. This process is called ovulation. If it meets sperm along the way, the egg may be fertilized, and the resulting fertilized egg soon begins to divide and differentiate into multiple cells while continuing its journey to the uterus. The lining of the uterus has become thicker and enriched with blood and nutrients. When the fertilized egg reaches its destination, it can easily implant itself into the uterine wall and begin to grow into an infant. If the egg is not fertilized, it still continues its journey into the uterus. In the absence of a hormonal message fertilization has occurred, the uterus ends its preparations for pregnancy and discards the endometrial lining it has built up, as well as the extra blood and nutrients it has amassed. This familiar event is known as menstruation. Once menstruation starts to lose its regularity this may mean the body is entering perimenopause. A cessation of periods completely means that the body has entered the state known as menopause.

The Hormones

As the body enters the state of menopause, first passing through perimenopause the ovaries begin to produce hormones in smaller amounts. Estrogen and progesterone are the most significantly affected, but androgen is also affected though not to the extent of the other two. Estrogen and progesterone in their reduced levels are often the cause of shorter, irregular cycles and the beginning of perimenopause.

Estrogen

Estrogen is a combination of three primary estrogens: Estriol, Estradiol, and Estrone. Estrogen is responsible for the development of most the female specific traits, i.e. breasts, vulva, etc. Estradiol is the strongest of the estrogens, responsible for ovulation and menstruation. Estrone is more important after the menopause and Estriol is manufactured from the placenta and fetus during pregnancy. Estrogens lower the risk of cardio vascular disease and help prevent osteoporosis. Conversely, too much estrogen can present a heightened breast cancer risk and a carcinoma of the cervix.

Progesterone
Progesterone is the dominant reproductive hormone during the last portion of the menstrual cycle. A lack of progesterone can cause a wide range of problems. The primary task of this hormone is to prepare the body for reproduction. Progesterone stimulates the growth of the endometrial lining and prepares breast tissue for the production of milk. Progesterone receptors are found mostly in reproductive organs. While estrogen continues to be produced at significant levels throughout a woman’s’ entire life, progesterone is drastically reduced after menopause. Progesterone counteracts many of the effects of Estrogen and is therefore often used in concert during Hormone Replacement Therapies. Progesterone helps mitigate the effects of Hot Flashes and PMS.

Androgen
Androgens are believed to contribute to sexual desire along with enhancing energy levels and a sense of well-being. They also contribute to bone growth and the functioning of the brain and eye along with a variety of other functions. Androgen also accentuates several characteristics during menopause such as facial hair and deeper voice. While androgen levels drop during menopause they do not drop as significantly as estrogen, thus accounting for their increased presence in comparison to other hormones.

Hormone Replacement Therapy

Hormone Replacement Therapy has been used for close to four decades now. While it seems to help the body towards a natural state of equilibrium and seems to counteract some of the more debilitative effects of perimenopause, there are a significant number of side effects to such treatments.

Most have PMS-like side effects and additionally often are accompanied by an increased risk of stroke, breast and ovarian cancer, high blood pressure, weight gain and fluid retention, mood swings and depression. There are many different medications and therapies available, some concentrating solely on estrogen replacement, others offering combinative treatments involving estrogen, progesterone and androgen. Certain risk factors such as high blood pressure, hypoglycemia and other factors should be taken into account before embarking on any replacement therapy and definitely a primary healthcare provider should be involved in the decision making process.

Non-Hormonal Therapies
If the prospect of adding more chemicals, pills, creams, gels and other foreign additives into the swirling mixture of your body’s chemistry which already seems chaotic at best, then there are alternative methods use to help relieve and accentuate the body’s natural losses. The intent of these procedures is just the same as that of Hormone Replacement Therapy; to assist the body towards a state of equilibrium it will reach at menopause and to make that transition as smooth as possible by alleviating the suffering caused by side effects. There are many creams do reduce vaginal dryness, along with hypertensive drugs that should reduce hot flashes. Incontinence can be treated through electrical stimulation or collagen implants. Bone loss can be treated with medications ranging from Fosamax to calcitonin. Also Bisphosphonates can be used also for bone loss.
In closing, an understanding of the major parts hormones play throughout the life of a woman, from puberty through all phases of her life up to and including post menopause is vitally important. A body well managed will help to alleviate some of the pressure the menopausal woman will experience as her body moves through the journey towards the state of menopause.

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